(Orexin is a neurotransmitter that helps regulate your sleep and wake states.) The hypothalamus in the brain releases orexin to help stimulate other brain regions to help keep you awake. Here are some possibilities:įor narcolepsy: The exact cause is uncertain, but may relate to a loss of orexin signaling for some people. Staying active may help you fight the urge to sleep.įor fatigue: There is often an underlying cause.
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